Expectation for "condition improvement" of skin aging

The five major factors leading to skin aging are said to be "photoaging", "oxidation", "dryness" "skin thinning" and " saccharification”.
In order to preserve the youthful "skin condition", it is important to know these five major factors, and take countermeasures and good care of your skin every day.
So, the question is if we take measures against these five major factors, will we be able to stop skin aging?

The answer is "NO".

The fundamental cause of skin aging is "telomeres shortening of skin cells". The five major causes of skin aging are caused by the acceleration of "telomere shortening" in skin cells.

"defytime TAA cream" is blended with high-class ingredients from the world and is the first aging care cream compounded with telomere activation molecule【TAM】, with the purpose to suppress this fundamental cause of “telomere shortening”, and it’s the ultimate aging care cream that can expect "condition improvement" of skin aging.

☞ Recommended for people like this

  • Looking at the mirror, I began to miss the skin of my twenties.
  • I would like to look younger than my actual age.
  • I want to tighten the sagging skin under my chin.
  • I want to get rid of the wrinkles in the corner of my eyes.
  • Recently, I am particularly concerned with my smile lines.
  • I want to regain skin firmness.
  • I want to improve my skin so my make-up looks good.
  • Cosmetic treatment/surgery is a little scary, and I was looking for something different.

☞ "defytime TAA cream" understood by video

Video time: 4 minutes 08 seconds

How To Use

The feeling of elasticity by moisture is aimed at over 1 month.

Recommend daily, twice a day in the morning and evening

The amount to apply on your skin depends on which part you apply the cream, but usually one push will be a sufficient amount.
If you use one push twice a day in the morning and evening, the cream will last for approximately 50 days.

For effective use ...

"defytime TAA cream" is not an all-in-one cream, so please combine it with your current cosmetics. Also, it is even more effective if you use ultrasonic facial equipment or duma roller when applying the cream because it will penetrate deeper into the skin.

Please note that it is fat soluble.

Since "defytime TAA cream" is fat-soluble, we recommend using it in the order of "lotion" → "beauty essence" → "cream" after cleansing your face. Please note that lotion will be repelled if you apply the cream first.

Recommendation by the Institute for Advanced Telomere Medicine

I am also very interested.

I have been advising anti-aging and aging treatment to many people. For women, "beauty" is an eternal theme, and it is very natural to want to be beautiful forever. Many people want to become beautiful and tend to care more about the appearance and features when they are young, but did you know that "skin quality" is also an important point to be considered as beautiful in the first impression?
If you age, you will inevitably suffer from aging phenomena on your skin such as spots and wrinkles, skin dullness, etc. due to cell aging. Continuous skin care is required for skin aging countermeasures.
"Persistence" is necessary ... Among such circumstances, I think "defytime TAA cream" and "Defytime the First" which compounds "TAM" and which suppresses cellular aging is very effective for particularly skin tightness and skin around the eyes.

Dr. Eijyu ASHIDA

Frequently Asked Questions

  1. Q1.What are the characteristics?
    It is the first aging care cream in the world to blend the latest telomerase activating molecule [TAM] that was developed by Dr. Bill Andrews, a pioneer of disease treatment due to aging and through many years of research.
  2. Q2.Can it get rid of wrinkles, spots, and sagging skin?
    Although there seems to be individual differences, the reports from "Avici Research Laboratory" from Italy which performs various clinical trials such as overseas famous cosmetics has confirmed improvement of wrinkles, spots and sagging skin through clinical trials.
  3. Q3.How long do you use it?
    Please consider using it a month or more to feel the moisture and firmness of the skin.
    The condition of your skin will change depending to the seasons and environmental influences, so it may take several months to feel the difference. We recommend you continue using it.
  4. Q4.Is it okay to use it other than your face and neck?
    "defytime TAA cream" is a product made for the purpose of using it on your face and neck, but there is no problem to use it on other parts.
  5. Q5.When should you apply to skin?
    We recommend daily use, twice a day in the morning and evening.
    After washing your face, use it in the order of "lotion" → "beauty essence" → "cream".
  6. Q6.How much cream should I apply?
    The amount to apply on your skin depends on which part you put in on, but usually one push (appox.0.5g) will be a sufficient amount.
    In addition, it is even more effective if you use ultrasonic facial equipments or duma roller when applying the cream because it will penetrate deeper into the skin.
  7. Q7.If I use “defytime TAA cream”, does it mean I don’t have to use other creams?
    "defytime TAA cream" has a mechanism to induce telomerase activity of the cells with [TAM].
    It is more effective if you use it in combination with the cosmetics you are currently using.
  8. Q8. I have sensitive skin and I’m concerned about side effects...
    In the clinical trials at Avichi Institute there were no reports of side effects, but please make sure to do a patch test before usage.
    Since this product contains more than 95% of natural ingredients, there is a possibility that it does not go along with your skin, but it’s rare to happen.
  9. Q9. I got something like red spots where I put on the cream…
    It seems that there are many cases in which it gets familiar with your skin by using a small amount every few days. Please try it once. However, there seem to be cases where symptoms appear due to insufficient sleep, stress, vitamin deficiency etc. Please refrain from using it when your physical condition is bad, and wait until recovery to use the cream again.
  10. Q10.How should I store it?
    Please keep away from direct sunlight, hot and humid places.
    Also, please follow the notes attached to the product after opening, and use it as soon as possible. Please refrain from using if you feel separation, deterioration, discoloration, odor, etc.
  11. Q11.Do you ship overseas?
    We are sorry, but currently we do not ship internationally.
  12. Q12.Do you have samples?
    We are sorry,but currently we do not prepare samples.

About purchase

For purchase from outside Japan, please contact us.