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Business background of "defytime"

In 2007, aging rate has reached 21.5%, and in Japan, which has entered the first in the world to the "super-aged society" , aging rate is about 30 percent in 2025, to 2060 It viewed and will reach about 40%.
Of human beings in 2045 after 30 years due to the rapid progress of the "elucidation of the aging mechanism," "evolution of cancer research," "the advent of predictive medicine," "dramatic modernization of regenerative medicine," such as medical technology life is the more than 100-year-old with a number of researchers have predicted.
It is gratifying story that life is extended, but on the other hand I have been found to also result in some problems, such as "reduced production of age population," "increase in social security costs," "increased care burden" in.

About Average life & Health expectancy

Japan of "average life" in 2014, according to the Ministry of Health, Labour and Welfare, men 80.50-year-old, women has become a 86.83-year-old. Woman is the third consecutive year in the world, if a man also third place, Japan will also say the world of longevity country.
By the way in life, apart from the here announced that have been "average life", and there is a thing called minus the number of years of the period of time that can not be independent living from the average life "healthy life expectancy" Do you know is that you are?
In simple terms it will be called "period in which the need to live healthy without any of the long-term care."

Healthy life expectancy of 2013, men 71.19 years (average life of the same year is 80.21 years old), women and 74.21 years (the same year the average life expectancy 86.61 years), men 9.02 years, there is a difference of some women 12.40 years's the actual situation .

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Prospects in the field of medicine

There are many people in the world today suffering from diseases caused by "telomere shortening."
You could even say that it is actually difficult to find diseases among scientific review that are not affected by “telomere.”
For example, even the development cancer and heart disease is influenced by telomere shortening.

※Diseases caused by telomere shortening  >>> List

Some people living on Earth are born with short telomere, and this condition is called Hutchinson-Gilford progeria syndrome (commonly known as progeria).
Children with progeria run around, chat and laugh like other children. But children with progeria have an average life expectancy of around 14 years, and nearly all die before the age of 20.
If there were a way to prevent telomere shortening, it would be possible to cure this disease.
The incidence rate of “progeria” is said to be 1 in 4,000,000. When looking at the world as a whole, this may seem like just a few children. But even now at this moment, there are children suffering from "progeria."
We are promoting product development because we think that discovering a way to cure progeria through our research would have great significance to these children.

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Prospects in the field of health

Health is defined in the Constitution of the World Health Organization (WHO) as follows: “Health is the state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.”
Against the background of becoming a super-aged society with increasing average life expectancies, what does it mean to possess physical and mental well-being?


Everyone wants to “stay healthy forever” and “be as energetic as when they were young”…
However, in reality, there exists a gap between “health expectancy” and “average life expectancy” of approximately 9 years for men and 12 years for women. This means it is difficult to maintain physical and mental well-being the entire time one is alive.

Against this background, we are promoting projects because we want to close the gap between “health expectancy” and “average life expectancy” through our research and the TAM-818 product.

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